20:45 Roma – Inter Milan

• The only defensive position where Roma don't have injury concerns is at left-back, where Ashley Cole and Jose Holebas are in competition for a starting spot.
• Maicon is a doubt with a knee problem, but he will probably start as Vasilis Torosidis is out.
• Despite problems in defence, Rudi Garcia can count on a number of players in midfield and attack, with Kevin Strootman finally available for selection.

Inter

• Roberto Mancini is likely to go on with the same centre-back pairing from the Milan Derby stalemate, meaning Nemanja Vidic will start on the bench.
• The former Manchester United defender has a minor physical problem that could put his trip to Rome in doubt.
• Zdravko Kuzmanovic may have earned a starting spot in the capital after scoring in the Europa League.
• Roma have secured back-to-back victories in Serie A, but missed the chance to pick up a victory against CSKA in midweek, meaning they need a win against Manchester City to secure a place in the knockout stages of the Champions League.
• Inter managed to avoid defeat in the derby after going 1-0 down, and then came from a goal down in the Europa League to defeat Dnipro despite finishing the game with 10 men. Roberto Mancini's arrival may boosted morale, but the technical side still needs to improve.
• Inter's current run under Mancini can't determine how they will fare against Roma, but Mancini needs his players to hit the ground running at the Olimpico rather than start slowly as they have done in their last two games, where they conceced the first goal on both occasions.
• Roma will look to strike early. A strong start should catch Inter unawares, which could help them over the 90 minutes following a tiring week.