The 76ers were one of the worst team in the league last season. Indiana still is one of the favorites to win the title this season even thou the lost Stephenson and Granger. I expect Roy Hibbert to have a big impact in this game.
I think the Pacers at home should be well capable of defeating the 76ers with about 10 or even more. -7 seems like the minimum they will lead half time. Based on these two meetings history I will go with Indiana, the Pacers has won 4 out of their last 4 meetings against the 76ers in the NBA.